How poisons enter the body and its clinical features-Poisoning

How poisons enter the body and its clinical features- Poisoning

A poison is a substance that, if taken into the body in sufficient quantity, can cause temporary or permanent damage or even death. Poisoning is a condition caused by introduction of harmful substances into the body by injection, ingestion, or inhalation. A poison may be taken by a person accidentally, for suicidal purpose, or be given to a person with homicidal purpose. Once a poison enters the body, it gets absorbed into the bloodstream and exerts its actions. The clinical features depend on the poison and its method entry

How poisons enter the body

A poison may enter the human body by any of the following routes.

  1. Oral route: swallowed poisons get absorbed through the walls of the digestive tract.
  2. Injection; poisons injected by intravenous, subcutaneous, or intramuscular route enter the blood stream rapidly. Snakes and insects may inject their venom into the skin by biting.
  3. Inhalation: poisonous gases may be inhaled. They get absorbed through the alveolar epithelium into the pulmonary capillaries. Examples are carbon monoxide, chemical vapors, fumes from fire, and exhaust engines.
  4. Through skin: chemicals like corrosives and pesticides may get absorbed through intact.

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